Mammalian Glutaminase Gls2 Gene Encodes Two Functional Alternative Transcripts by a Surrogate Promoter Usage Mechanism

BACKGROUND: Glutaminase is expressed in most mammalian tissues and cancer cells, but the regulation of its expression is poorly understood. An essential step to accomplish this goal is the characterization of its species- and cell-specific isoenzyme pattern of expression. Our aim was to identify and...

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Detalles Bibliográficos
Autores principales: Martín-Rufián, Mercedes, Tosina, Marta, Campos-Sandoval, José A., Manzanares, Elisa, Lobo, Carolina, Segura, J. A., Alonso, Francisco J., Matés, José M., Márquez, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367983/
https://www.ncbi.nlm.nih.gov/pubmed/22679499
http://dx.doi.org/10.1371/journal.pone.0038380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367983/
https://www.ncbi.nlm.nih.gov/pubmed/22679499
http://dx.doi.org/10.1371/journal.pone.0038380

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