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Probing a Polar Cluster in the Retinal Binding Pocket of Bacteriorhodopsin by a Chemical Design Approach

Bacteriorhodopsin has a polar cluster of amino acids surrounding the retinal molecule, which is responsible for light harvesting to fuel proton pumping. From our previous studies, we have shown that threonine 90 is the pivotal amino acid in this polar cluster, both functionally and structurally. In...

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Detalles Bibliográficos
Autores principales: Simón-Vázquez, Rosana, Domínguez, Marta, Lórenz-Fonfría, Víctor A., Álvarez, Susana, Bourdelande, José-Luís, de Lera, Ángel R., Padrós, Esteve, Perálvarez-Marín, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411786/
https://www.ncbi.nlm.nih.gov/pubmed/22879987
http://dx.doi.org/10.1371/journal.pone.0042447