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Simultaneous RNA quantification of human and retroviral genomes reveals intact interferon signaling in HTLV-1-infected CD4+ T cell lines

BACKGROUND: IFN-α contributes extensively to host immune response upon viral infection through antiviral, pro-apoptotic, antiproliferative and immunomodulatory activities. Although extensively documented in various types of human cancers and viral infections, controversy exists in the exact mechanis...

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Detalles Bibliográficos
Autores principales: Moens, Britta, Pannecouque, Christophe, López, Giovanni, Talledo, Michael, Gotuzzo, Eduardo, Khouri, Ricardo, Bittencourt, Achiléa, Farré, Lourdes, Galvão-Castro, Bernardo, Vandamme, Anne-Mieke, Van Weyenbergh, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492208/
https://www.ncbi.nlm.nih.gov/pubmed/22917064
http://dx.doi.org/10.1186/1743-422X-9-171