Functional role of post-translational modifications of Sp1 in tumorigenesis

Specific protein 1 (Sp1), the first transcription factor to be isolated, regulates the expression of numerous genes involved in cell proliferation, apoptosis, and differentiation. Recent studies found that an increase in Sp1 transcriptional activity is associated with the tumorigenesis. Moreover, po...

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Detalles Bibliográficos
Autores principales: Chang, Wen-Chang, Hung, Jan-Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3503885/
https://www.ncbi.nlm.nih.gov/pubmed/23148884
http://dx.doi.org/10.1186/1423-0127-19-94