Thermally Targeted Delivery of a c-Myc Inhibitory Polypeptide Inhibits Tumor Progression and Extends Survival in a Rat Glioma Model

Treatment of glioblastoma is complicated by the tumors’ high resistance to chemotherapy, poor penetration of drugs across the blood brain barrier, and damaging effects of chemotherapy and radiation to normal neural tissue. To overcome these limitations, a thermally responsive polypeptide was develop...

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Detalles Bibliográficos
Autores principales: Bidwell, Gene L., Perkins, Eddie, Hughes, Joshua, Khan, Majid, James, Judy R., Raucher, Drazen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3555869/
https://www.ncbi.nlm.nih.gov/pubmed/23372821
http://dx.doi.org/10.1371/journal.pone.0055104