Soluble Guanylyl Cyclase Is Reduced in Airway Smooth Muscle Cells From a Murine Model of Allergic Asthma

Airway remodeling plays an important role in the development of airway hyperresponsiveness in asthma. Muscarinic agonists such as carbamylcholine increased cyclic GMP (cGMP) levels in bovine tracheal smooth muscle strips, via stimulation of NO-sensitive soluble guanylylcyclase (NO-sGC), which is an...

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Detalles Bibliográficos
Autores principales: Placeres-Uray, Fabiola, de Alfonzo, Ramona González, de Becemberg, Itala Lippo, Alfonzo, Marcelo J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: World Allergy Organization 2010
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651105/
https://www.ncbi.nlm.nih.gov/pubmed/23282985
http://dx.doi.org/10.1097/WOX.0b013e318201d80b

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