MYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma

MYCN is a master regulator controlling many processes necessary for tumor cell survival. Here, we unravel a microRNA network that causes tumor suppressive effects in MYCN-amplified neuroblastoma cells. In profiling studies, histone deacetylase (HDAC) inhibitor treatment most strongly induced miR-183...

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Detalles Bibliográficos
Autores principales: Lodrini, Marco, Oehme, Ina, Schroeder, Christina, Milde, Till, Schier, Marie C., Kopp-Schneider, Annette, Schulte, Johannes H., Fischer, Matthias, De Preter, Katleen, Pattyn, Filip, Castoldi, Mirco, Muckenthaler, Martina U., Kulozik, Andreas E., Westermann, Frank, Witt, Olaf, Deubzer, Hedwig E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695529/
https://www.ncbi.nlm.nih.gov/pubmed/23625969
http://dx.doi.org/10.1093/nar/gkt346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695529/
https://www.ncbi.nlm.nih.gov/pubmed/23625969
http://dx.doi.org/10.1093/nar/gkt346

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