Evaluation of genetic risk score models in the presence of interaction and linkage disequilibrium

In the area of genetic epidemiology, genetic risk predictive modeling is becoming an important area of translational success. As an increasing number of genetic variants are successfully discovered, the use of multiple genetic variants in constructing a genetic risk score (GRS) for modeling has been...

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Detalles Bibliográficos
Autores principales: Che, Ronglin, Motsinger-Reif, Alison A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719135/
https://www.ncbi.nlm.nih.gov/pubmed/23888168
http://dx.doi.org/10.3389/fgene.2013.00138