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MHC genotyping of non-model organisms using next-generation sequencing: a new methodology to deal with artefacts and allelic dropout

BACKGROUND: The Major Histocompatibility Complex (MHC) is the most important genetic marker to study patterns of adaptive genetic variation determining pathogen resistance and associated life history decisions. It is used in many different research fields ranging from human medical, molecular evolut...

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Detalles Bibliográficos
Autores principales: Sommer, Simone, Courtiol, Alexandre, Mazzoni, Camila J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750822/
https://www.ncbi.nlm.nih.gov/pubmed/23937623
http://dx.doi.org/10.1186/1471-2164-14-542