MiR-27a Regulates Apoptosis in Nucleus Pulposus Cells by Targeting PI3K

The precise role of apoptosis in the pathogenesis of intervertebral disc degeneration (IDD) remains to be elucidated. We analyzed degenerative nucleus pulposus (NP) cells and found that the expression of miR-27a was increased. The overexpression of miR-27a was further verified using real-time RT-PCR...

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Detalles Bibliográficos
Autores principales: Liu, Gang, Cao, Peng, Chen, Huajiang, Yuan, Wen, Wang, Jianxi, Tang, Xianye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783482/
https://www.ncbi.nlm.nih.gov/pubmed/24086481
http://dx.doi.org/10.1371/journal.pone.0075251