CX3CL1 at the crossroad of EGF signals: Relevance for the progression of ERBB2(+) breast carcinoma

Inflammatory mediators can play a dual role in oncogenesis and tumor progression. CX3CL1, a chemokine previously implicated in natural killer cell- and CD8(+) T cell-mediated antitumor immune responses, has now been identified as a promoter of ERBB2-expressing breast carcinomas as it cross-activates...

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Detalles Bibliográficos
Autores principales: Tardáguila, Manuel, Mañes, Santos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850216/
https://www.ncbi.nlm.nih.gov/pubmed/24319638
http://dx.doi.org/10.4161/onci.25669
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author Tardáguila, Manuel
Mañes, Santos
author_facet Tardáguila, Manuel
Mañes, Santos
author_sort Tardáguila, Manuel
collection PubMed
description Inflammatory mediators can play a dual role in oncogenesis and tumor progression. CX3CL1, a chemokine previously implicated in natural killer cell- and CD8(+) T cell-mediated antitumor immune responses, has now been identified as a promoter of ERBB2-expressing breast carcinomas as it cross-activates members of the epidermal growth factor receptor family.
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spelling pubmed-38502162013-12-07 CX3CL1 at the crossroad of EGF signals: Relevance for the progression of ERBB2(+) breast carcinoma Tardáguila, Manuel Mañes, Santos Oncoimmunology Author's View Inflammatory mediators can play a dual role in oncogenesis and tumor progression. CX3CL1, a chemokine previously implicated in natural killer cell- and CD8(+) T cell-mediated antitumor immune responses, has now been identified as a promoter of ERBB2-expressing breast carcinomas as it cross-activates members of the epidermal growth factor receptor family. Landes Bioscience 2013-09-01 2013-07-09 /pmc/articles/PMC3850216/ /pubmed/24319638 http://dx.doi.org/10.4161/onci.25669 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Tardáguila, Manuel
Mañes, Santos
CX3CL1 at the crossroad of EGF signals: Relevance for the progression of ERBB2(+) breast carcinoma
title CX3CL1 at the crossroad of EGF signals: Relevance for the progression of ERBB2(+) breast carcinoma
title_full CX3CL1 at the crossroad of EGF signals: Relevance for the progression of ERBB2(+) breast carcinoma
title_fullStr CX3CL1 at the crossroad of EGF signals: Relevance for the progression of ERBB2(+) breast carcinoma
title_full_unstemmed CX3CL1 at the crossroad of EGF signals: Relevance for the progression of ERBB2(+) breast carcinoma
title_short CX3CL1 at the crossroad of EGF signals: Relevance for the progression of ERBB2(+) breast carcinoma
title_sort cx3cl1 at the crossroad of egf signals: relevance for the progression of erbb2(+) breast carcinoma
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850216/
https://www.ncbi.nlm.nih.gov/pubmed/24319638
http://dx.doi.org/10.4161/onci.25669
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