Elevated serum fibroblast growth factor 21 levels correlate with immune recovery but not mitochondrial dysfunction in HIV infection

BACKGROUND: Anti-retroviral treated HIV-infected patients are at risk of mitochondrial toxicity, but non-invasive markers are lacking. Serum FGF-21 (fibroblast growth factor 21) levels correlate strongly with muscle biopsy findings in inherited mitochondrial disorders. We therefore aimed to determin...

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Detalles Bibliográficos
Autores principales: Payne, Brendan AI, Price, David Ashley, Chinnery, Patrick F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874602/
https://www.ncbi.nlm.nih.gov/pubmed/24252301
http://dx.doi.org/10.1186/1742-6405-10-27