A Primer on Effectiveness and Efficacy Trials

Although efficacy and effectiveness studies are both important when evaluating interventions, they serve distinct purposes and have different study designs. Unfortunately, the distinction between these two types of trials is often poorly understood. In this primer, we highlight several differences b...

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Detalles Bibliográficos
Autores principales: Singal, Amit G, Higgins, Peter D R, Waljee, Akbar K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912314/
https://www.ncbi.nlm.nih.gov/pubmed/24384867
http://dx.doi.org/10.1038/ctg.2013.13
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author Singal, Amit G
Higgins, Peter D R
Waljee, Akbar K
author_facet Singal, Amit G
Higgins, Peter D R
Waljee, Akbar K
author_sort Singal, Amit G
collection PubMed
description Although efficacy and effectiveness studies are both important when evaluating interventions, they serve distinct purposes and have different study designs. Unfortunately, the distinction between these two types of trials is often poorly understood. In this primer, we highlight several differences between these two types of trials including study design, patient populations, intervention design, data analysis, and result reporting.
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spelling pubmed-39123142014-02-04 A Primer on Effectiveness and Efficacy Trials Singal, Amit G Higgins, Peter D R Waljee, Akbar K Clin Transl Gastroenterol Clinical/Narrative Review Although efficacy and effectiveness studies are both important when evaluating interventions, they serve distinct purposes and have different study designs. Unfortunately, the distinction between these two types of trials is often poorly understood. In this primer, we highlight several differences between these two types of trials including study design, patient populations, intervention design, data analysis, and result reporting. Nature Publishing Group 2014-01 2014-01-02 /pmc/articles/PMC3912314/ /pubmed/24384867 http://dx.doi.org/10.1038/ctg.2013.13 Text en Copyright © 2014 American College of Gastroenterology http://creativecommons.org/licenses/by-nc-nd/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/
spellingShingle Clinical/Narrative Review
Singal, Amit G
Higgins, Peter D R
Waljee, Akbar K
A Primer on Effectiveness and Efficacy Trials
title A Primer on Effectiveness and Efficacy Trials
title_full A Primer on Effectiveness and Efficacy Trials
title_fullStr A Primer on Effectiveness and Efficacy Trials
title_full_unstemmed A Primer on Effectiveness and Efficacy Trials
title_short A Primer on Effectiveness and Efficacy Trials
title_sort primer on effectiveness and efficacy trials
topic Clinical/Narrative Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912314/
https://www.ncbi.nlm.nih.gov/pubmed/24384867
http://dx.doi.org/10.1038/ctg.2013.13
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