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A Comparison Between GATE and MCNPX Monte Carlo Codes in Simulation of Medical Linear Accelerator

Radiotherapy dose calculations can be evaluated by Monte Carlo (MC) simulations with acceptable accuracy for dose prediction in complicated treatment plans. In this work, Standard, Livermore and Penelope electromagnetic (EM) physics packages of GEANT4 application for tomographic emission (GATE) 6.1...

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Autores principales: Sadoughi, Hamid-Reza, Nasseri, Shahrokh, Momennezhad, Mahdi, Sadeghi, Hamid-Reza, Bahreyni-Toosi, Mohammad-Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967451/
https://www.ncbi.nlm.nih.gov/pubmed/24696804
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author Sadoughi, Hamid-Reza
Nasseri, Shahrokh
Momennezhad, Mahdi
Sadeghi, Hamid-Reza
Bahreyni-Toosi, Mohammad-Hossein
author_facet Sadoughi, Hamid-Reza
Nasseri, Shahrokh
Momennezhad, Mahdi
Sadeghi, Hamid-Reza
Bahreyni-Toosi, Mohammad-Hossein
author_sort Sadoughi, Hamid-Reza
collection PubMed
description Radiotherapy dose calculations can be evaluated by Monte Carlo (MC) simulations with acceptable accuracy for dose prediction in complicated treatment plans. In this work, Standard, Livermore and Penelope electromagnetic (EM) physics packages of GEANT4 application for tomographic emission (GATE) 6.1 were compared versus Monte Carlo N-Particle eXtended (MCNPX) 2.6 in simulation of 6 MV photon Linac. To do this, similar geometry was used for the two codes. The reference values of percentage depth dose (PDD) and beam profiles were obtained using a 6 MV Elekta Compact linear accelerator, Scanditronix water phantom and diode detectors. No significant deviations were found in PDD, dose profile, energy spectrum, radial mean energy and photon radial distribution, which were calculated by Standard and Livermore EM models and MCNPX, respectively. Nevertheless, the Penelope model showed an extreme difference. Statistical uncertainty in all the simulations was <1%, namely 0.51%, 0.27%, 0.27% and 0.29% for PDDs of 10 cm(2)× 10 cm(2) filed size, for MCNPX, Standard, Livermore and Penelope models, respectively. Differences between spectra in various regions, in radial mean energy and in photon radial distribution were due to different cross section and stopping power data and not the same simulation of physics processes of MCNPX and three EM models. For example, in the Standard model, the photoelectron direction was sampled from the Gavrila-Sauter distribution, but the photoelectron moved in the same direction of the incident photons in the photoelectric process of Livermore and Penelope models. Using the same primary electron beam, the Standard and Livermore EM models of GATE and MCNPX showed similar output, but re-tuning of primary electron beam is needed for the Penelope model.
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spelling pubmed-39674512014-04-02 A Comparison Between GATE and MCNPX Monte Carlo Codes in Simulation of Medical Linear Accelerator Sadoughi, Hamid-Reza Nasseri, Shahrokh Momennezhad, Mahdi Sadeghi, Hamid-Reza Bahreyni-Toosi, Mohammad-Hossein J Med Signals Sens Original Article Radiotherapy dose calculations can be evaluated by Monte Carlo (MC) simulations with acceptable accuracy for dose prediction in complicated treatment plans. In this work, Standard, Livermore and Penelope electromagnetic (EM) physics packages of GEANT4 application for tomographic emission (GATE) 6.1 were compared versus Monte Carlo N-Particle eXtended (MCNPX) 2.6 in simulation of 6 MV photon Linac. To do this, similar geometry was used for the two codes. The reference values of percentage depth dose (PDD) and beam profiles were obtained using a 6 MV Elekta Compact linear accelerator, Scanditronix water phantom and diode detectors. No significant deviations were found in PDD, dose profile, energy spectrum, radial mean energy and photon radial distribution, which were calculated by Standard and Livermore EM models and MCNPX, respectively. Nevertheless, the Penelope model showed an extreme difference. Statistical uncertainty in all the simulations was <1%, namely 0.51%, 0.27%, 0.27% and 0.29% for PDDs of 10 cm(2)× 10 cm(2) filed size, for MCNPX, Standard, Livermore and Penelope models, respectively. Differences between spectra in various regions, in radial mean energy and in photon radial distribution were due to different cross section and stopping power data and not the same simulation of physics processes of MCNPX and three EM models. For example, in the Standard model, the photoelectron direction was sampled from the Gavrila-Sauter distribution, but the photoelectron moved in the same direction of the incident photons in the photoelectric process of Livermore and Penelope models. Using the same primary electron beam, the Standard and Livermore EM models of GATE and MCNPX showed similar output, but re-tuning of primary electron beam is needed for the Penelope model. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC3967451/ /pubmed/24696804 Text en Copyright: © Journal of Medical Signals and Sensors http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Sadoughi, Hamid-Reza
Nasseri, Shahrokh
Momennezhad, Mahdi
Sadeghi, Hamid-Reza
Bahreyni-Toosi, Mohammad-Hossein
A Comparison Between GATE and MCNPX Monte Carlo Codes in Simulation of Medical Linear Accelerator
title A Comparison Between GATE and MCNPX Monte Carlo Codes in Simulation of Medical Linear Accelerator
title_full A Comparison Between GATE and MCNPX Monte Carlo Codes in Simulation of Medical Linear Accelerator
title_fullStr A Comparison Between GATE and MCNPX Monte Carlo Codes in Simulation of Medical Linear Accelerator
title_full_unstemmed A Comparison Between GATE and MCNPX Monte Carlo Codes in Simulation of Medical Linear Accelerator
title_short A Comparison Between GATE and MCNPX Monte Carlo Codes in Simulation of Medical Linear Accelerator
title_sort comparison between gate and mcnpx monte carlo codes in simulation of medical linear accelerator
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967451/
https://www.ncbi.nlm.nih.gov/pubmed/24696804
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