Different Roles for the Axin Interactions with the SAMP versus the Second Twenty Amino Acid Repeat of Adenomatous Polyposis Coli

Wnt signalling is prevented by the proteosomal degradation of β-catenin, which occurs in a destruction complex containing adenomatous polyposis coli (APC), APC-like (APCL), Axin and Axin2. Truncating mutations of the APC gene result in the constitutive stabilisation of β-catenin and the initiation o...

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Detalles Bibliográficos
Autores principales: Schneikert, Jean, Ruppert, Jan Gustav, Behrens, Jürgen, Wenzel, Eva Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983206/
https://www.ncbi.nlm.nih.gov/pubmed/24722208
http://dx.doi.org/10.1371/journal.pone.0094413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983206/
https://www.ncbi.nlm.nih.gov/pubmed/24722208
http://dx.doi.org/10.1371/journal.pone.0094413

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