Discovery of a Dicer-Independent, Cell-Type Dependent Alternate Targeting Sequence Generator: Implications in Gene Silencing & Pooled RNAi Screens

There is an acceptance that plasmid-based delivery of interfering RNA always generates the intended targeting sequences in cells, making it as specific as its synthetic counterpart. However, recent studies have reported on cellular inefficiencies of the former, especially in light of emerging gene d...

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Detalles Bibliográficos
Autores principales: Bhinder, Bhavneet, Shum, David, Li, Mu, Ibáñez, Glorymar, Vlassov, Alexander V., Magdaleno, Susan, Djaballah, Hakim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079264/
https://www.ncbi.nlm.nih.gov/pubmed/24987961
http://dx.doi.org/10.1371/journal.pone.0100676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079264/
https://www.ncbi.nlm.nih.gov/pubmed/24987961
http://dx.doi.org/10.1371/journal.pone.0100676

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