Calpain 1 inhibitor BDA-410 ameliorates α-klotho-deficiency phenotypes resembling human aging-related syndromes

Taking good care of elderly is a major challenge of our society, and thus identification of potential drug targets to reduce age-associated disease burden is desirable. α-klotho(-/-) (α-kl) is a short-lived mouse model that displays multiple phenotypes resembling human aging-related syndromes. Such...

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Detalles Bibliográficos
Autores principales: Nabeshima, Yoko, Washida, Miwa, Tamura, Masaru, Maeno, Akiteru, Ohnishi, Mutsuko, Shiroishi, Toshihiko, Imura, Akihiro, Razzaque, M. Shawkat, Nabeshima, Yo-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118420/
https://www.ncbi.nlm.nih.gov/pubmed/25080854
http://dx.doi.org/10.1038/srep05847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118420/
https://www.ncbi.nlm.nih.gov/pubmed/25080854
http://dx.doi.org/10.1038/srep05847

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