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RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma

The 'gold standard' for oncogenic HPV detection is the demonstration of transcriptionally active high-risk HPV in tumor tissue. However, detection of E6/E7 mRNA by quantitative reverse transcription polymerase chain reaction (qRT-PCR) requires RNA extraction which destroys the tumor tissue...

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Detalles Bibliográficos
Autores principales: Wang, Hongwei, Wang, Mindy Xiao-Ming, Su, Nan, Wang, Li-chong, Wu, Xingyong, Bui, Son, Nielsen, Allissa, Vo, Hong-Thuy, Nguyen, Nina, Luo, Yuling, Ma, Xiao-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145807/
https://www.ncbi.nlm.nih.gov/pubmed/24637627
http://dx.doi.org/10.3791/51426