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Chimeric antigen receptor for adoptive immunotherapy of cancer: latest research and future prospects
Chimeric antigen receptors (CARs) are recombinant receptors that combine the specificity of an antigen-specific antibody with the T-cell’s activating functions. Initial clinical trials of genetically engineered CAR T cells have significantly raised the profile of T cell therapy, and great efforts ha...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177696/ https://www.ncbi.nlm.nih.gov/pubmed/25241075 http://dx.doi.org/10.1186/1476-4598-13-219 |