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Chimeric antigen receptor for adoptive immunotherapy of cancer: latest research and future prospects

Chimeric antigen receptors (CARs) are recombinant receptors that combine the specificity of an antigen-specific antibody with the T-cell’s activating functions. Initial clinical trials of genetically engineered CAR T cells have significantly raised the profile of T cell therapy, and great efforts ha...

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Detalles Bibliográficos
Autores principales: Shi, Huan, Sun, Meili, Liu, Lin, Wang, Zhehai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177696/
https://www.ncbi.nlm.nih.gov/pubmed/25241075
http://dx.doi.org/10.1186/1476-4598-13-219