The Binding of Apolipoprotein E to Oligomers and Fibrils of Amyloid-β Alters the Kinetics of Amyloid Aggregation

[Image: see text] Deposition of amyloid-β (Aβ) in Alzheimer’s disease (AD) is strongly correlated with the APOE genotype. However, the role of apolipoprotein E (apoE) in Aβ aggregation has remained unclear. Here we have used different apoE preparations, such as recombinant protein or protein isolate...

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Detalles Bibliográficos
Autores principales: Garai, Kanchan, Verghese, Philip B., Baban, Berevan, Holtzman, David M., Frieden, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196732/
https://www.ncbi.nlm.nih.gov/pubmed/25207746
http://dx.doi.org/10.1021/bi5008172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196732/
https://www.ncbi.nlm.nih.gov/pubmed/25207746
http://dx.doi.org/10.1021/bi5008172

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