Oral carvedilol in escalating doses in the acute treatment of atrial fibrillation

OBJECTIVE: To study the efficacy of oral carvedilol in acute treatment of atrial fibrillation (AF) with fast ventricular rate. MATERIALS AND METHODS: In an open-label, single-arm trial, oral carvedilol was administered to 35 patients of AF in escalating doses from 3.125 mg o.d. to 12.5 mg b.i.d. RES...

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Autores principales: Chitrapu, Ravi Venkatachelam, Rao, Pentakota Ramana, Reddy, Gangireddy Venkateswara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231552/
https://www.ncbi.nlm.nih.gov/pubmed/25422563
http://dx.doi.org/10.4103/0976-500X.142430
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author Chitrapu, Ravi Venkatachelam
Rao, Pentakota Ramana
Reddy, Gangireddy Venkateswara
author_facet Chitrapu, Ravi Venkatachelam
Rao, Pentakota Ramana
Reddy, Gangireddy Venkateswara
author_sort Chitrapu, Ravi Venkatachelam
collection PubMed
description OBJECTIVE: To study the efficacy of oral carvedilol in acute treatment of atrial fibrillation (AF) with fast ventricular rate. MATERIALS AND METHODS: In an open-label, single-arm trial, oral carvedilol was administered to 35 patients of AF in escalating doses from 3.125 mg o.d. to 12.5 mg b.i.d. RESULTS: A successful result was seen in 25 patients (71.4%) with 4 converting to sinus rhythm, rate control to less than 90 bpm in 16 and a 20% rate reduction in 5 patients. Two patients developed hypotension needing withdrawal of the drug. CONCLUSION: Escalating doses of oral carvedilol can be effectively and safely used in the acute treatment of AF with fast ventricular rate.
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spelling pubmed-42315522014-11-24 Oral carvedilol in escalating doses in the acute treatment of atrial fibrillation Chitrapu, Ravi Venkatachelam Rao, Pentakota Ramana Reddy, Gangireddy Venkateswara J Pharmacol Pharmacother Research Paper OBJECTIVE: To study the efficacy of oral carvedilol in acute treatment of atrial fibrillation (AF) with fast ventricular rate. MATERIALS AND METHODS: In an open-label, single-arm trial, oral carvedilol was administered to 35 patients of AF in escalating doses from 3.125 mg o.d. to 12.5 mg b.i.d. RESULTS: A successful result was seen in 25 patients (71.4%) with 4 converting to sinus rhythm, rate control to less than 90 bpm in 16 and a 20% rate reduction in 5 patients. Two patients developed hypotension needing withdrawal of the drug. CONCLUSION: Escalating doses of oral carvedilol can be effectively and safely used in the acute treatment of AF with fast ventricular rate. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4231552/ /pubmed/25422563 http://dx.doi.org/10.4103/0976-500X.142430 Text en Copyright: © Journal of Pharmacology and Pharmacotherapeutics http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Paper
Chitrapu, Ravi Venkatachelam
Rao, Pentakota Ramana
Reddy, Gangireddy Venkateswara
Oral carvedilol in escalating doses in the acute treatment of atrial fibrillation
title Oral carvedilol in escalating doses in the acute treatment of atrial fibrillation
title_full Oral carvedilol in escalating doses in the acute treatment of atrial fibrillation
title_fullStr Oral carvedilol in escalating doses in the acute treatment of atrial fibrillation
title_full_unstemmed Oral carvedilol in escalating doses in the acute treatment of atrial fibrillation
title_short Oral carvedilol in escalating doses in the acute treatment of atrial fibrillation
title_sort oral carvedilol in escalating doses in the acute treatment of atrial fibrillation
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231552/
https://www.ncbi.nlm.nih.gov/pubmed/25422563
http://dx.doi.org/10.4103/0976-500X.142430
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AT reddygangireddyvenkateswara oralcarvedilolinescalatingdosesintheacutetreatmentofatrialfibrillation

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