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Recombinant factor VIIa analog in the management of hemophilia with inhibitors: results from a multicenter, randomized, controlled trial of vatreptacog alfa
BACKGROUND: Vatreptacog alfa, a recombinant factor VIIa (rFVIIa) analog with three amino acid substitutions and 99% identity to native FVIIa, was developed to improve the treatment of hemophilic patients with inhibitors. OBJECTIVES: To confirm the safety and assess the efficacy of vatreptacog alfa i...
Autores principales: | Lentz, S R, Ehrenforth, S, Abdul Karim, F, Matsushita, T, Weldingh, K N, Windyga, J, Mahlangu, J N, For the Adept™2 Investigators |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238784/ https://www.ncbi.nlm.nih.gov/pubmed/24931322 http://dx.doi.org/10.1111/jth.12634 |
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