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The Type 2 Diabetes Risk Allele of TMEM154-rs6813195 Associates with Decreased Beta Cell Function in a Study of 6,486 Danes

OBJECTIVES: A trans-ethnic meta-analysis of type 2 diabetes genome-wide association studies has identified seven novel susceptibility variants in or near TMEM154, SSR1/RREB1, FAF1, POU5F1/TCF19, LPP, ARL15 and ABCB9/MPHOSPH9. The aim of our study was to investigate associations between these novel r...

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Detalles Bibliográficos
Autores principales: Harder, Marie Neergaard, Appel, Emil Vincent Rosenbaum, Grarup, Niels, Gjesing, Anette Prior, Ahluwalia, Tarunveer S., Jørgensen, Torben, Christensen, Cramer, Brandslund, Ivan, Linneberg, Allan, Sørensen, Thorkild I. A., Pedersen, Oluf, Hansen, Torben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370672/
https://www.ncbi.nlm.nih.gov/pubmed/25799151
http://dx.doi.org/10.1371/journal.pone.0120890