Development of a Cell-Based Bioassay for Phospholipase A(2)-Triggered Liposomal Drug Release

The feasibility of exploiting secretory phospholipase A(2) (sPLA(2)) enzymes, which are overexpressed in tumors, to activate drug release from liposomes precisely at the tumor site has been demonstrated before. Although the efficacy of the developed formulations was evaluated using in vitro and in v...

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Detalles Bibliográficos
Autores principales: Arouri, Ahmad, Trojnar, Jakub, Schmidt, Steffen, Hansen, Anders H., Mollenhauer, Jan, Mouritsen, Ole G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422686/
https://www.ncbi.nlm.nih.gov/pubmed/25945937
http://dx.doi.org/10.1371/journal.pone.0125508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422686/
https://www.ncbi.nlm.nih.gov/pubmed/25945937
http://dx.doi.org/10.1371/journal.pone.0125508

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