Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary, Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein

Prevention efforts for respiratory syncytial virus (RSV) have been advanced due to the recent isolation and characterization of antibodies that specifically recognize the prefusion conformation of the RSV fusion (F) glycoprotein. These potently neutralizing antibodies are in clinical development for...

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Detalles Bibliográficos
Autores principales: Gilman, Morgan S. A., Moin, Syed M., Mas, Vicente, Chen, Man, Patel, Nita K., Kramer, Kari, Zhu, Qing, Kabeche, Stephanie C., Kumar, Azad, Palomo, Concepción, Beaumont, Tim, Baxa, Ulrich, Ulbrandt, Nancy D., Melero, José A., Graham, Barney S., McLellan, Jason S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498696/
https://www.ncbi.nlm.nih.gov/pubmed/26161532
http://dx.doi.org/10.1371/journal.ppat.1005035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498696/
https://www.ncbi.nlm.nih.gov/pubmed/26161532
http://dx.doi.org/10.1371/journal.ppat.1005035

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