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Embryonic MicroRNA-369 Controls Metabolic Splicing Factors and Urges Cellular Reprograming
Noncoding microRNAs inhibit translation and lower the transcript stability of coding mRNA, however miR-369 s, in aberrant silencing genomic regions, stabilizes target proteins under cellular stress. We found that in vitro differentiation of embryonic stem cells led to chromatin methylation of histon...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503752/ https://www.ncbi.nlm.nih.gov/pubmed/26176628 http://dx.doi.org/10.1371/journal.pone.0132789 |