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Defining the roles of arrestin2 and arrestin3 in vasoconstrictor receptor desensitization in hypertension
Prolonged vasoconstrictor-stimulated phospholipase C activity can induce arterial constriction, hypertension, and smooth muscle hypertrophy/hyperplasia. Arrestin proteins are recruited by agonist-occupied G protein-coupled receptors to terminate signaling and counteract changes in vascular tone. Her...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525080/ https://www.ncbi.nlm.nih.gov/pubmed/25972452 http://dx.doi.org/10.1152/ajpcell.00079.2015 |