Age-related sensitivity to endotoxin-induced liver inflammation: Implication of inflammasome/IL-1β for steatohepatitis

Aging is associated with increased vulnerability to inflammatory challenge. However, the effects of altered inflammatory response on the metabolic status of tissues or organs are not well documented. In this study, we present evidence demonstrating that lipopolysaccharide (LPS)-induced upregulation...

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Detalles Bibliográficos
Autores principales: Chung, Ki Wung, Lee, Eun Kyeong, Kim, Dae Hyun, An, Hye Jin, Kim, Nam Deuk, Im, Dong Soon, Lee, Jaewon, Yu, Byung Pal, Chung, Hae Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531067/
https://www.ncbi.nlm.nih.gov/pubmed/25847140
http://dx.doi.org/10.1111/acel.12305