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A Simple Proteomics-Based Approach to Identification of Immunodominant Antigens from a Complex Pathogen: Application to the CD4 T Cell Response against Human Herpesvirus 6B

Most of humanity is chronically infected with human herpesvirus 6 (HHV-6), with viral replication controlled at least in part by a poorly characterized CD4 T cell response. Identification of viral epitopes recognized by CD4 T cells is complicated by the large size of the herpesvirus genome and a low...

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Detalles Bibliográficos
Autores principales: Becerra-Artiles, Aniuska, Dominguez-Amorocho, Omar, Stern, Lawrence J., Calvo-Calle, J. Mauricio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658110/
https://www.ncbi.nlm.nih.gov/pubmed/26599878
http://dx.doi.org/10.1371/journal.pone.0142871