KCTD12 Regulates Colorectal Cancer Cell Stemness through the ERK Pathway

Targeting cancer stem cells (CSCs) in colorectal cancer (CRC) remains a difficult problem, as the regulation of CSCs in CRC is poorly understood. Here we demonstrated that KCTD12, potassium channel tetramerization domain containing 12, is down-regulated in the CSC-like cells of CRC. The silencing of...

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Detalles Bibliográficos
Autores principales: Li, Liping, Duan, Tingmei, Wang, Xin, Zhang, Ru-Hua, Zhang, Meifang, Wang, Suihai, Wang, Fen, Wu, Yuanzhong, Huang, Haojie, Kang, Tiebang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742820/
https://www.ncbi.nlm.nih.gov/pubmed/26847701
http://dx.doi.org/10.1038/srep20460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742820/
https://www.ncbi.nlm.nih.gov/pubmed/26847701
http://dx.doi.org/10.1038/srep20460

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