Cytomegalovirus-Infected Cells Resist T Cell Mediated Killing in an HLA-Recognition Independent Manner

In order to explore the potential of HLA-independent T cell therapy for human cytomegalovirus (HCMV) infections, we developed a chimeric antigen receptor (CAR) directed against the HCMV encoded glycoprotein B (gB), which is expressed at high levels on the surface of infected cells. T cells engineere...

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Detalles Bibliográficos
Autores principales: Proff, Julia, Walterskirchen, Christian, Brey, Charlotte, Geyeregger, Rene, Full, Florian, Ensser, Armin, Lehner, Manfred, Holter, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899442/
https://www.ncbi.nlm.nih.gov/pubmed/27375569
http://dx.doi.org/10.3389/fmicb.2016.00844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899442/
https://www.ncbi.nlm.nih.gov/pubmed/27375569
http://dx.doi.org/10.3389/fmicb.2016.00844

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