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Darwinolide, a New Diterpene Scaffold That Inhibits Methicillin-Resistant Staphylococcus aureus Biofilm from the Antarctic Sponge Dendrilla membranosa

[Image: see text] A new rearranged spongian diterpene, darwinolide, has been isolated from the Antarctic Dendroceratid sponge Dendrilla membranosa. Characterized on the basis of spectroscopic and crystallographic analysis, the central seven-membered ring is hypothesized to originate from a ring-expa...

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Detalles Bibliográficos
Autores principales: von Salm, Jacqueline L., Witowski, Christopher G., Fleeman, Renee M., McClintock, James B., Amsler, Charles D., Shaw, Lindsey N., Baker, Bill J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928490/
https://www.ncbi.nlm.nih.gov/pubmed/27175857
http://dx.doi.org/10.1021/acs.orglett.6b00979