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Dynamic changes of driver genes’ mutations across clinical stages in nine cancer types
The driver genes play critical roles for tumorigenesis, and the number of identified driver genes reached plateau. But how they act during different cancer development stages is lack of knowledge. We investigated 138 driver genes’ mutation changes across clinical stages using 3,477 cases in nine can...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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John Wiley and Sons Inc.
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944883/ https://www.ncbi.nlm.nih.gov/pubmed/26992457 http://dx.doi.org/10.1002/cam4.704 |