Cargando…

Dynamic changes of driver genes’ mutations across clinical stages in nine cancer types

The driver genes play critical roles for tumorigenesis, and the number of identified driver genes reached plateau. But how they act during different cancer development stages is lack of knowledge. We investigated 138 driver genes’ mutation changes across clinical stages using 3,477 cases in nine can...

Descripción completa

Detalles Bibliográficos
Autor principal: Li, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944883/
https://www.ncbi.nlm.nih.gov/pubmed/26992457
http://dx.doi.org/10.1002/cam4.704