Frequent occurrence of large duplications at reciprocal genomic rearrangement breakpoints in multiple myeloma and other tumors

Using a combination of array comparative genomic hybridization, mate pair and cloned sequences, and FISH analyses, we have identified in multiple myeloma cell lines and tumors a novel and recurrent type of genomic rearrangement, i.e. interchromosomal rearrangements (translocations or insertions) and...

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Detalles Bibliográficos
Autores principales: Demchenko, Yulia, Roschke, Anna, Chen, Wei-Dong, Asmann, Yan, Bergsagel, Peter Leif, Kuehl, Walter Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041460/
https://www.ncbi.nlm.nih.gov/pubmed/27353332
http://dx.doi.org/10.1093/nar/gkw527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041460/
https://www.ncbi.nlm.nih.gov/pubmed/27353332
http://dx.doi.org/10.1093/nar/gkw527

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