MKEY, a Peptide Inhibitor of CXCL4‐CCL5 Heterodimer Formation, Protects Against Stroke in Mice

BACKGROUND: MKEY, a synthetic cyclic peptide inhibitor of CXCL4–CCL5 heterodimer formation, has been shown to protect against atherosclerosis and aortic aneurysm formation by mediating inflammation, but whether it modulates neuroinflammation and brain injury has not been studied. We therefore studie...

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Detalles Bibliográficos
Autores principales: Fan, Yifang, Xiong, Xiaoxing, Zhang, Yongming, Yan, Dongmei, Jian, Zhihong, Xu, Baohui, Zhao, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079025/
https://www.ncbi.nlm.nih.gov/pubmed/27633389
http://dx.doi.org/10.1161/JAHA.116.003615