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Design, implementation and evaluation of a practical pseudoknot folding algorithm based on thermodynamics

BACKGROUND: The general problem of RNA secondary structure prediction under the widely used thermodynamic model is known to be NP-complete when the structures considered include arbitrary pseudoknots. For restricted classes of pseudoknots, several polynomial time algorithms have been designed, where...

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Detalles Bibliográficos
Autores principales: Reeder, Jens, Giegerich, Robert
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC514697/
https://www.ncbi.nlm.nih.gov/pubmed/15294028
http://dx.doi.org/10.1186/1471-2105-5-104