Extremely Rare Polymorphisms in Saccharomyces cerevisiae Allow Inference of the Mutational Spectrum

The characterization of mutational spectra is usually carried out in one of three ways–by direct observation through mutation accumulation (MA) experiments, through parent-offspring sequencing, or by indirect inference from sequence data. Direct observations of spontaneous mutations with MA experime...

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Detalles Bibliográficos
Autores principales: Zhu, Yuan O., Sherlock, Gavin, Petrov, Dmitri A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207638/
https://www.ncbi.nlm.nih.gov/pubmed/28046117
http://dx.doi.org/10.1371/journal.pgen.1006455