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In vitro generation of Sertoli-like and haploid spermatid-like cells from human umbilical cord perivascular cells

BACKGROUND: First trimester (FTM) and term human umbilical cord-derived perivascular cells (HUCPVCs), which are rich sources of mesenchymal stem cells (MSCs), can give rise to Sertoli cell (SC)-like as well as haploid germ cell (GC)-like cells in vitro using culture conditions that recapitulate the...

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Detalles Bibliográficos
Autores principales: Shlush, Ekaterina, Maghen, Leila, Swanson, Sonja, Kenigsberg, Shlomit, Moskovtsev, Sergey, Barretto, Tanya, Gauthier-Fisher, Andrée, Librach, Clifford L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312448/
https://www.ncbi.nlm.nih.gov/pubmed/28202061
http://dx.doi.org/10.1186/s13287-017-0491-8