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Angiotensin-(1-7) Downregulates Diabetes-Induced cGMP Phosphodiesterase Activation in Rat Corpus Cavernosum

Molecular mechanisms of the beneficial effects of angiotensin-(1-7), Ang-(1-7), in diabetes-related complications, including erectile dysfunction, remain unclear. We examined the effect of diabetes and/or Ang-(1-7) treatment on vascular reactivity and cyclic guanosine monophosphate (cGMP) phosphodie...

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Detalles Bibliográficos
Autores principales: Dhaunsi, Gursev S., Yousif, Mariam, Makki, Batoul, Akhtar, Saghir, Benter, Ibrahim F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337337/
https://www.ncbi.nlm.nih.gov/pubmed/28299329
http://dx.doi.org/10.1155/2017/5084961