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Galectin-3 inhibition ameliorates hypoxia-induced pulmonary artery hypertension
Galectin-3 (Gal-3) is a β-galactoside-binding lectin, which is important in inflammation, fibrosis and heart failure. The present study aimed to investigate the role and mechanism of Gal-3 in hypoxia-induced pulmonary arterial hypertension (PAH). Male C57BL/6J and Gal-3(−/−) mice were exposed to hyp...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355711/ https://www.ncbi.nlm.nih.gov/pubmed/27959409 http://dx.doi.org/10.3892/mmr.2016.6020 |