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Galectin-3 inhibition ameliorates hypoxia-induced pulmonary artery hypertension

Galectin-3 (Gal-3) is a β-galactoside-binding lectin, which is important in inflammation, fibrosis and heart failure. The present study aimed to investigate the role and mechanism of Gal-3 in hypoxia-induced pulmonary arterial hypertension (PAH). Male C57BL/6J and Gal-3(−/−) mice were exposed to hyp...

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Detalles Bibliográficos
Autores principales: Hao, Mingwen, Li, Miaomiao, Li, Wenjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355711/
https://www.ncbi.nlm.nih.gov/pubmed/27959409
http://dx.doi.org/10.3892/mmr.2016.6020