KDM3A coordinates actin dynamics with intraflagellar transport to regulate cilia stability

Cilia assembly and disassembly are coupled to actin dynamics, ensuring a coherent cellular response during environmental change. How these processes are integrated remains undefined. The histone lysine demethylase KDM3A plays important roles in organismal homeostasis. Loss-of-function mouse models o...

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Detalles Bibliográficos
Autores principales: Yeyati, Patricia L., Schiller, Rachel, Mali, Girish, Kasioulis, Ioannis, Kawamura, Akane, Adams, Ian R., Playfoot, Christopher, Gilbert, Nick, van Heyningen, Veronica, Wills, Jimi, von Kriegsheim, Alex, Finch, Andrew, Sakai, Juro, Schofield, Christopher J., Jackson, Ian J., Mill, Pleasantine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379941/
https://www.ncbi.nlm.nih.gov/pubmed/28246120
http://dx.doi.org/10.1083/jcb.201607032