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The Combination of Computational and Biosensing Technologies for Selecting Aptamer against Prostate Specific Antigen

Herein, we report a method of combining bioinformatics and biosensing technologies to select aptamers against prostate specific antigen (PSA). The main objective of this study is to select DNA aptamers with higher binding affinity for PSA by using the proposed method. Based on the five known sequenc...

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Detalles Bibliográficos
Autores principales: Hsieh, Pi-Chou, Lin, Hui-Ting, Chen, Wen-Yih, Tsai, Jeffrey J. P., Hu, Wen-Pin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387809/
https://www.ncbi.nlm.nih.gov/pubmed/28459059
http://dx.doi.org/10.1155/2017/5041683