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Adult teleost heart expresses two distinct troponin C paralogs: cardiac TnC and a novel and teleost-specific ssTnC in a chamber- and temperature-dependent manner

The teleost-specific whole genome duplication created multiple copies of genes allowing for subfunctionalization of isoforms. In this study, we show that the teleost cardiac Ca(2+)-binding troponin C (TnC) is the product of two distinct genes: cardiac TnC (cTnC, TnnC1a) and a fish-specific slow skel...

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Detalles Bibliográficos
Autores principales: Genge, Christine E., Davidson, William S., Tibbits, Glen F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471341/
https://www.ncbi.nlm.nih.gov/pubmed/23881286
http://dx.doi.org/10.1152/physiolgenomics.00074.2013