Targeted CDX2 expression inhibits aggressive phenotypes of colon cancer cells in vitro and in vivo

Loss of caudal type homeobox 2 (CDX2) is associated with the development of human colorectal cancer, while human telomerase reverse transcriptase (hTERT) frequently occurs in variety of human cancers. We investigated the effects of restoration of CDX2 expression using a hypoxia-inducible hTERT promo...

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Detalles Bibliográficos
Autores principales: Zheng, Jianbao, He, Sai, Qi, Jie, Wang, Xiaolong, Yu, Junhui, Wu, Yunhua, Gao, Qi, Wang, Kai, Sun, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505129/
https://www.ncbi.nlm.nih.gov/pubmed/28627695
http://dx.doi.org/10.3892/ijo.2017.4040