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In vitro expansion impaired the stemness of early passage mesenchymal stem cells for treatment of cartilage defects
In vitro cultured autologous mesenchymal stem cells (MSCs) within passage 5 have been approved for clinical application in stem cell-based treatment of cartilage defects. However, their chondrogenic potential has not yet been questioned or verified. In this study, the chondrogenic potential of bone...
Autores principales: | Jiang, Tongmeng, Xu, Guojie, Wang, Qiuyan, Yang, Lihui, Zheng, Li, Zhao, Jinmin, Zhang, Xingdong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520885/ https://www.ncbi.nlm.nih.gov/pubmed/28569773 http://dx.doi.org/10.1038/cddis.2017.215 |
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