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In vitro expansion impaired the stemness of early passage mesenchymal stem cells for treatment of cartilage defects

In vitro cultured autologous mesenchymal stem cells (MSCs) within passage 5 have been approved for clinical application in stem cell-based treatment of cartilage defects. However, their chondrogenic potential has not yet been questioned or verified. In this study, the chondrogenic potential of bone...

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Detalles Bibliográficos
Autores principales: Jiang, Tongmeng, Xu, Guojie, Wang, Qiuyan, Yang, Lihui, Zheng, Li, Zhao, Jinmin, Zhang, Xingdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520885/
https://www.ncbi.nlm.nih.gov/pubmed/28569773
http://dx.doi.org/10.1038/cddis.2017.215

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