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Anti-complement component 5 antibody targeting MG4 domain inhibits choroidal neovascularization

Age-related macular degeneration (AMD) is one of the main causes of visual impairment in adults. Visual deterioration is more prominent in neovascular AMD with choroidal neovascularization (CNV). Clinical and postmortem studies suggested that complement system activation might induce CNV. In this st...

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Detalles Bibliográficos
Autores principales: Jo, Dong Hyun, Kim, Jin Hyoung, Yang, Wonjun, Kim, Hyori, Chang, Shinjae, Kim, Dongjo, Chang, Minseok, Lee, Kihwang, Chung, Junho, Kim, Jeong Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542204/
https://www.ncbi.nlm.nih.gov/pubmed/28477014
http://dx.doi.org/10.18632/oncotarget.17221