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Dissecting Amyloid Beta Deposition Using Distinct Strains of the Neurotropic Parasite Toxoplasma gondii as a Novel Tool

Genetic and pathologic data suggest that amyloid beta (Aβ), produced by processing of the amyloid precursor protein, is a major initiator of Alzheimer’s disease (AD). To gain new insights into Aβ modulation, we sought to harness the power of the coevolution between the neurotropic parasite Toxoplasm...

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Detalles Bibliográficos
Autores principales: Cabral, Carla M., McGovern, Kathryn E., MacDonald, Wes R., Franco, Jenna, Koshy, Anita A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565021/
https://www.ncbi.nlm.nih.gov/pubmed/28817954
http://dx.doi.org/10.1177/1759091417724915