Regulation of human and mouse telomerase genes by genomic contexts and transcription factors during embryonic stem cell differentiation

Differential regulation of telomerase reverse transcriptase (TERT) genes contribute to distinct aging and tumorigenic processes in humans and mice. To study TERT regulation, we generated mouse embryonic stem cell (ESC) lines containing single-copy bacterial artificial chromosome (BAC) reporters, cov...

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Detalles Bibliográficos
Autores principales: Cheng, De, Wang, Shuwen, Jia, Wenwen, Zhao, Yuanjun, Zhang, Fan, Kang, Jiuhong, Zhu, Jiyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703907/
https://www.ncbi.nlm.nih.gov/pubmed/29180668
http://dx.doi.org/10.1038/s41598-017-16764-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703907/
https://www.ncbi.nlm.nih.gov/pubmed/29180668
http://dx.doi.org/10.1038/s41598-017-16764-w

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