WWC2 is an independent prognostic factor and prevents invasion via Hippo signalling in hepatocellular carcinoma

WWC family proteins negatively regulate HEK293 cell proliferation and organ growth by suppressing the transcriptional activity of Yes‐associated protein (YAP), a major effector of the Hippo pathway. The function of the scaffolding protein WWC1 (also called KIBRA) has been intensively studied in cell...

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Detalles Bibliográficos
Autores principales: Zhang, Yijun, Yan, Shumei, Chen, Jiewei, Gan, Caixia, Chen, Dong, Li, Yan, Wen, Jiahuai, Kremerskothen, Joachim, Chen, Shilu, Zhang, Jiangbo, Cao, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706493/
https://www.ncbi.nlm.nih.gov/pubmed/28815883
http://dx.doi.org/10.1111/jcmm.13281