WWC2 is an independent prognostic factor and prevents invasion via Hippo signalling in hepatocellular carcinoma
WWC family proteins negatively regulate HEK293 cell proliferation and organ growth by suppressing the transcriptional activity of Yes‐associated protein (YAP), a major effector of the Hippo pathway. The function of the scaffolding protein WWC1 (also called KIBRA) has been intensively studied in cell...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706493/ https://www.ncbi.nlm.nih.gov/pubmed/28815883 http://dx.doi.org/10.1111/jcmm.13281 |