Spectrum of mutations in monogenic diabetes genes identified from high-throughput DNA sequencing of 6888 individuals

BACKGROUND: Diagnosis of monogenic as well as atypical forms of diabetes mellitus has important clinical implications for their specific diagnosis, prognosis, and targeted treatment. Single gene mutations that affect beta-cell function represent 1–2% of all cases of diabetes. However, phenotypic het...

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Detalles Bibliográficos
Autores principales: Bansal, Vikas, Gassenhuber, Johann, Phillips, Tierney, Oliveira, Glenn, Harbaugh, Rebecca, Villarasa, Nikki, Topol, Eric J., Seufferlein, Thomas, Boehm, Bernhard O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717832/
https://www.ncbi.nlm.nih.gov/pubmed/29207974
http://dx.doi.org/10.1186/s12916-017-0977-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717832/
https://www.ncbi.nlm.nih.gov/pubmed/29207974
http://dx.doi.org/10.1186/s12916-017-0977-3

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